CARBOLIEVA 150MG ( Carboplatin Injection IP 150mg )

CARBOLIEVA 150 mg contains Carboplatin, a platinum-based chemotherapy (anticancer) drug. It works by forming DNA cross-links, which inhibit DNA synthesis and repair, leading to cancer cell death. Compared to cisplatin, carboplatin has less nephrotoxicity and neurotoxicity.

Carboplatin Injection is used in the treatment of:

1. Ovarian cancer

2. Non-small cell lung cancer (NSCLC)

3. Small cell lung cancer

4. Head and neck cancers

5. Breast cancer

6. Cervical and other gynecological cancers
   (often used in combination chemotherapy)

Common side effects:

• Myelosuppression (especially thrombocytopenia)

• Nausea and vomiting

• Fatigue, weakness

• Electrolyte imbalance

• Mild hair loss

Serious side effects:

• Severe bone marrow suppression

• Allergic/hypersensitivity reactions (especially after multiple cycles)

• Kidney function impairment

• Ototoxicity (hearing problems)

 Regular CBC and kidney function monitoring is essential.

Dosage is individualized based on renal function and AUC (Calvert formula).

Common dosing methods:

• AUC 4–6 IV on Day 1 of each cycle (every 3–4 weeks)

• Alternative: 300–400 mg/m² IV every 4 weeks

 Given as intravenous infusion under oncologist supervision.