CISLIEVA 10 mg contains Cisplatin, a platinum-based chemotherapy (anticancer) drug. It works by forming DNA cross-links, which inhibit DNA synthesis and repair, leading to death of rapidly dividing cancer cells. Cisplatin is a cornerstone drug in many solid tumor chemotherapy regimens.

Cisplatin Injection is used in the treatment of:

1. Testicular cancer

2. Ovarian cancer

3. Bladder cancer

4. Head and neck cancers

5. Lung cancer (NSCLC & SCLC)

6. Cervical cancer

7. Gastric and esophageal cancers

Common side effects:

• Severe nausea and vomiting

• Nephrotoxicity (kidney damage)

• Ototoxicity (hearing loss, tinnitus)

• Myelosuppression

• Electrolyte imbalance (low magnesium, potassium)

• Peripheral neuropathy

Serious side effects:

• Severe kidney failure

• Severe hearing loss

• Anaphylactic reactions

• Neurotoxicity

Adequate hydration and electrolyte monitoring are mandatory during cisplatin therapy.

Dosage depends on body surface area (BSA) and treatment protocol.

Common regimens:

• 50–100 mg/m² IV every 3–4 weeks

• 20 mg/m²/day IV for 5 consecutive days (every 3–4 weeks)

Administered as slow intravenous infusion with pre- and post-hydration under oncologist supervision.