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Product Details

Crizotinib Tablets 250mg

Crizotinib Tablets 250mg


Brand NameCRIZLIEVA 250MG
CompositionCrizotinib Tablets 250mg
Manufacture ByAllieva Pharma Private Limited
FormTablet
PackingBtl (60Tab)
Country Of OriginIndia

Description

Description

CRIZLIEVA 250 mg contains Crizotinib, an oral tyrosine kinase inhibitor (TKI). It targets ALK (anaplastic lymphoma kinase), ROS1, and MET receptors, inhibiting signaling pathways that drive tumor cell growth and survival. It is especially effective in ALK-positive and ROS1-positive lung cancers.

Uses

Crizotinib is indicated for:

1. Metastatic Non-Small Cell Lung Cancer (NSCLC)
    – ALK-positive disease
    – ROS1-positive disease

Side Effects

Common side effects:

    •  Visual disturbances (blurred vision, photopsia)

    •  Nausea, vomiting, diarrhea

    •  Fatigue

    •  Edema

Laboratory abnormalities:

    •  Elevated liver enzymes

Serious side effects:

    •  Hepatotoxicity

    •  QT interval prolongation

    •  Interstitial lung disease (rare)

    •  Bradycardia

 Regular monitoring of LFTs, ECG, and heart rate is advised.

Dosage

Standard adult dose:

    •  250 mg twice daily

 Continue treatment until disease progression or unacceptable toxicity.

 

NOTE: This medicine should be taken only under a doctor’s supervision.


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