Paclieva 300 mg contains Paclitaxel, a chemotherapy (anticancer) drug belonging to the taxane class. It works by stabilizing microtubules and preventing their depolymerization, which inhibits mitosis and leads to death of rapidly dividing cancer cells.

Paclitaxel Injection is used in the treatment of:

1. Breast cancer

2. Ovarian cancer

3. Non-small cell lung cancer (NSCLC)

4. AIDS-related Kaposi’s sarcoma

5. Head and neck cancers (in combination chemotherapy)

Common side effects:

• Hair loss (alopecia)

• Nausea, vomiting

• Myelosuppression (neutropenia, anemia, thrombocytopenia)

• Fatigue and weakness

• Muscle and joint pain

• Peripheral neuropathy (tingling, numbness)

Dosage is based on body surface area (BSA), type of cancer, and treatment protocol.

Common regimens:

• 175 mg/m² IV infusion over 3 hours every 3 weeks

• 135 mg/m² IV infusion over 24 hours every 3 weeks

• Weekly schedule: 80–100 mg/m² IV

NOTE: This medicine should be taken only under a doctor’s supervision.