Etoposide Injection IP 100MG
Etoposide is a semisynthetic podophyllotoxin derivative and a topoisomerase II inhibitor. It works by preventing DNA unwinding and replication in cancer cells, leading to cell death. Etoposide is widely used in various chemotherapy regimens for both solid tumors and hematological malignancies.
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Capecitabine Dispersible Tablets 500mg
CAPELIEVA-DT 500 mg contains Capecitabine, an oral fluoropyrimidine chemotherapy drug. It is a prodrug that converts into 5-Fluorouracil (5-FU) inside tumor cells, where it interferes with DNA synthesis and inhibits cancer cell growth.
The dispersible (DT) form is helpful for patients who have difficulty swallowing tablets.
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Irinotecan Hydrochloride Injection IP 100mg
IRILIEVA 100 mg contains Irinotecan Hydrochloride, a topoisomerase I inhibitor anticancer drug. It works by preventing DNA replication in rapidly dividing cancer cells, leading to cell death.
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Topotecan Injection IP 2.5mg
HYCALIEVA 2.5 mg contains Topotecan, a topoisomerase-I inhibitor belonging to the camptothecin class. It works by stabilizing the topoisomerase-I–DNA complex, causing DNA strand breaks and preventing DNA replication, leading to cancer cell death.
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Doxorubicin Hydrochloride iInjection IP 50mg
DOXLIEVA 50 mg contains Doxorubicin Hydrochloride, an anthracycline antitumor antibiotic. It acts by intercalating into DNA, inhibiting topoisomerase II, and generating free radicals, leading to DNA damage and apoptosis of cancer cells. It is a backbone drug in many chemotherapy regimens.
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Dactinomycin for Injection USP 0.5MG
DACTOLIEVA 0.5 mg contains Dactinomycin (Actinomycin D), an antitumor antibiotic. It works by intercalating into DNA, thereby inhibiting RNA synthesis and blocking protein production, leading to cancer cell death. It is especially effective in pediatric and germ cell tumors.
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Vinorelbine Injection IP 50mg
NAVELIEVA 50 mg contains Vinorelbine, a semi-synthetic vinca alkaloid. It inhibits microtubule assembly by binding to tubulin, thereby arresting cell division in the M phase of the cell cycle. It is primarily used in lung and breast cancers.
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Fludarabine Phosphate for Injection 10mg
FLULIEVA 10 mg contains Fludarabine Phosphate, a purine nucleoside analogue antimetabolite. Inside the cell, it is converted to the active metabolite fludarabine triphosphate, which inhibits DNA polymerase, ribonucleotide reductase, and DNA primase, leading to inhibition of DNA synthesis and apoptosis. It is primarily used in hematological malignancies.
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L-Asparaginase Injection 5000IU
L-GANASELIEVA 5,000 IU contains L-Asparaginase, an antineoplastic enzyme used mainly in leukemia treatment. It works by depleting the amino acid asparagine from the blood. Leukemic lymphoblasts cannot synthesize asparagine on their own, so depletion leads to inhibition of protein synthesis and cell death.
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L-Asparaginase Injection 10000IU
L-GANASELIEVA 10,000 IU contains L-Asparaginase, an antineoplastic enzyme. It works by depleting asparagine, an amino acid essential for leukemic lymphoblasts. Normal cells can synthesize asparagine, but leukemic cells cannot—leading to selective tumor cell death.
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Ifosfamide for Injection with Mesna 2g
IFOSLIEVA 2 g contains Ifosfamide, an alkylating antineoplastic agent (nitrogen mustard derivative), supplied with Mesna. Ifosfamide causes DNA cross-linking, inhibiting DNA replication and leading to cancer cell death. Mesna is co-administered to prevent hemorrhagic cystitis by neutralizing toxic metabolites (acrolein) in the urinary tract.
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Ifosfamide for Injection with Mesna 1g
IFOSLIEVA 1 g contains Ifosfamide, an alkylating antineoplastic agent (nitrogen mustard derivative), supplied with Mesna. Ifosfamide causes DNA cross-linking, inhibiting DNA replication and leading to cancer cell death. Mesna is co-administered to prevent hemorrhagic cystitis by binding toxic uro-metabolites (acrolein) in the urinary tract.
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